Abstract The role of Golgi/endosome-localized clathrin CS-1708 adapters in the maintenance of steady-state cell surface epidermal growth factor receptor (EGFR) is not well known.Here, we show that EGFR associates preferentially with both AP-1 and GGA2 in vitro.AP-1 depletion caused a reduction in the EGFR protein by promoting its lysosomal degradat
Abstract Since its founding a decade ago, Environmental Health has received more than one thousand manuscripts.Last year marked the first time we published over 100 articles.The journal web site currently receives over 60,000 unique visitors every month, and the steady increase suggests that the number Cleansing Oil will soon exceed 100,000 monthly
Abstract Background Osteoarthritis (OA) is a prevalent, chronic joint condition that commonly affects the knee and hip causing pain, impaired function, and reduced quality of life.As there is no cure, the main goal of treatment is to alleviate symptoms via ongoing self-management predominantly consisting of exercise and weight loss (if indicated).H